Summary of S1P receptor modulators currently undergoing or completed in... | Download Table
IJMS | Free Full-Text | Immune System and Brain/Intestinal Barrier Functions in Psychiatric Diseases: Is Sphingosine-1-Phosphate at the Helm?
PDF) First use of cenerimod, a selective S1P 1 receptor modulator, for the treatment of SLE: A double-blind, randomised, placebo-controlled, proof-of-concept study
IJMS | Free Full-Text | Unraveling the Link between Interferon-α and Systemic Lupus Erythematosus: From the Molecular Mechanisms to Target Therapies
Potent anti‐inflammatory properties of HDL in vascular smooth muscle cells mediated by HDL‐S1P and their impairment in coronary artery disease due to lower HDL‐S1P: a new aspect of HDL dysfunction and its
Sphingosine‐1‐phosphate receptor modulators in stroke treatment - Zhang - 2022 - Journal of Neurochemistry - Wiley Online Library
Functions and interaction of plant lipid signalling under abiotic stresses - Liang - 2023 - Plant Biology - Wiley Online Library
Targeting the Sphingosine Kinase/Sphingosine 1‐Phosphate Pathway to Treat Chronic Inflammatory Kidney Diseases - Schwalm - 2014 - Basic & Clinical Pharmacology & Toxicology - Wiley Online Library
Biomedicines | Free Full-Text | Sphingosine-1-Phosphate: Its Pharmacological Regulation and the Treatment of Multiple Sclerosis: A Review Article
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Potent anti‐inflammatory properties of HDL in vascular smooth muscle cells mediated by HDL‐S1P and their impairment in coronary artery disease due to lower HDL‐S1P: a new aspect of HDL dysfunction and its
Neutrophil recruitment mediated by sphingosine 1-phosphate (S1P)/S1P receptors during chronic liver injury - ScienceDirect
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The role of sphingosine-1-phosphate in autophagy and related disorders | Cell Death Discovery
Modulators of Sphingosine-1-phosphate Pathway Biology: Recent Advances of Sphingosine-1-phosphate Receptor 1 (S1P1) Agonists and Future Perspectives | Journal of Medicinal Chemistry
Sphingosine 1-phosphate (S1P) induces COX-2 expression and PGE2 formation via S1P receptor 2 in renal mesangial cells - ScienceDirect
Valproic acid enforces the priming effect of sphingosine-1 phosphate on human mesenchymal stem cells
IJMS | Free Full-Text | Lipids as Targets for Renal Cell Carcinoma Therapy
Biomedicines | Free Full-Text | Sphingosine-1-Phosphate: Its Pharmacological Regulation and the Treatment of Multiple Sclerosis: A Review Article
Cells | Free Full-Text | The S1P–S1PR Axis in Neurological Disorders—Insights into Current and Future Therapeutic Perspectives
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Neutrophil recruitment mediated by sphingosine 1-phosphate (S1P)/S1P receptors during chronic liver injury - ScienceDirect
Modulators of Sphingosine-1-phosphate Pathway Biology: Recent Advances of Sphingosine-1-phosphate Receptor 1 (S1P1) Agonists and Future Perspectives | Journal of Medicinal Chemistry
Sphingosine‐1‐phosphate receptor modulators in stroke treatment - Zhang - 2022 - Journal of Neurochemistry - Wiley Online Library
Bioactive Scaffolds as a Promising Alternative for Enhancing Critical-Size Bone Defect Regeneration in the Craniomaxillofacial Region | ACS Applied Bio Materials
Targeting the Sphingosine Kinase/Sphingosine 1‐Phosphate Pathway to Treat Chronic Inflammatory Kidney Diseases - Schwalm - 2014 - Basic & Clinical Pharmacology & Toxicology - Wiley Online Library
Implications of Sphingolipid Metabolites in Kidney Diseases. - Abstract - Europe PMC
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Whole Blood and Plasma-Based Lipid Profiling Reveals Distinctive Metabolic Changes in Systemic Lupus Erythematosus and Systemic Sclerosis | Journal of Proteome Research
![Discovery of the S1P2 Antagonist GLPG2938 (1-[2-Ethoxy-6-(trifluoromethyl)-4-pyridyl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea), a Preclinical Candidate for the Treatment of Idiopathic Pulmonary Fibrosis ...](https://pubs.acs.org/cms/10.1021/acs.jmedchem.1c00138/asset/images/medium/jm1c00138_0002.gif "Discovery of the S1P2 Antagonist GLPG2938 (1-[2-Ethoxy-6-(trifluoromethyl)-4-pyridyl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea), a Preclinical Candidate for the Treatment of Idiopathic Pulmonary Fibrosis ...")
Discovery of the S1P2 Antagonist GLPG2938 (1-[2-Ethoxy-6-(trifluoromethyl)-4-pyridyl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea), a Preclinical Candidate for the Treatment of Idiopathic Pulmonary Fibrosis ...
Immune Responses at Host Barriers and Their Importance in Systemic Autoimmune Diseases | SpringerLink
IJMS | Free Full-Text | Sphingosine 1-Phosphate as Essential Signaling Molecule in Inflammatory Skin Diseases
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Strategic outline of interventions targeting extracellular matrix for promoting healthy longevity | American Journal of Physiology-Cell Physiology
Cells | Free Full-Text | The S1P–S1PR Axis in Neurological Disorders—Insights into Current and Future Therapeutic Perspectives
PDF) Sphingosine-1-Phosphate (S1P) and S1P Signaling Pathway Modulators, from Current Insights to Future Perspectives
FTY720, a Synthetic Sphingosine 1 Phosphate Analogue, Inhibits Development of Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice | Circulation
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The role of sphingosine-1-phosphate in autophagy and related disorders | Cell Death Discovery
IJMS | Free Full-Text | A Rheostat of Ceramide and Sphingosine-1-Phosphate as a Determinant of Oxidative Stress-Mediated Kidney Injury
IJMS | Free Full-Text | A Rheostat of Ceramide and Sphingosine-1-Phosphate as a Determinant of Oxidative Stress-Mediated Kidney Injury
The role of sphingosine-1-phosphate in autophagy and related disorders | Cell Death Discovery
IJMS | Free Full-Text | A Rheostat of Ceramide and Sphingosine-1-Phosphate as a Determinant of Oxidative Stress-Mediated Kidney Injury
DAMPs in Systemic Autoimmune Diseases | SpringerLink
Sphingosine-1-Phosphate Metabolism and Signaling in Kidney Diseases. - Abstract - Europe PMC
Neutrophil recruitment mediated by sphingosine 1-phosphate (S1P)/S1P receptors during chronic liver injury - ScienceDirect
Chemical structures of sphingosine 1-phosphate, fingolimod, siponimod... | Download Scientific Diagram
